※ PP7 family introduction

    PP7, also known as PPEF phosphatase, is Ser/Thr phosphatases of the PPP family. The catalytic domain of PP7 is flanked by N- and C-terminal domain. PP7 is charactered by its EF-hand domain which is invloved in calcium-binding. This character suggests that PP7 can be regulated by Ca2+. In mammals, PP7 is found in various sensory neurons and might be invloved in sensory signalling. PP7 also acts as a regulator in cell growth, cell apoptosis, proliferation or oncogenic transformation (1).

Reference
1. Andreeva, A.V. and Kutuzov, M.A. (2009) PPEF/PP7 protein Ser/Thr phosphatases. Cell Mol Life Sci, 66, 3103-3110. PMID: 19662497

  Reviewed (0)  or Unreviewed (5) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sem-1415	SELMODRAFT_426688	D8SX64	PP7A-1
2		iEKPD-Sem-1418	SELMODRAFT_185987	D8T6U9	PP7A-2
3		iEKPD-Sem-1411	SELMODRAFT_12808	D8SX70	PP7B-1
4		iEKPD-Sem-1425	SELMODRAFT_429646	D8T6V0	PP7B-2
5		iEKPD-Sem-1413	SELMODRAFT_451287	D8SX66	PP7C-1