Ashbya gossypii      PPP/PPP_Unique


※ PPP_Unique family introduction

    Phosphoprotein phosphatase (PPP) is highly conserved among all eukaryotes. Seven phosphatases compose of PPP family in human genome, which are known as PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6 and PP7. PPP family phosphatases share a conserved catalytic domain ~280 amino acids and three signature motifs (-GDXHG-, -GDXVDRG- and -GNHE-) in its domain. The catalytic subunits of several members in PPP family always associate with a number of regulatory subunits, which regulate the substrate recognition and function. For PPP family members, metal ions play an important role during dephosphorylation reaction (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Asg-g008
AGOS_ABL181W
Q75E51
AGOS_ABL181W
2
iEKPD-Asg-0128
AGOS_AER265W
Q756X4
AGOS_AER265W
3
iEKPD-Asg-0129
AGOS_AER334C
Q756D3
AGOS_AER334C
4
iEKPD-Asg-0130
AGOS_AFL051W
Q754W8
AGOS_AFL051W