Physcomitrella patens      PPP/PPP_Unique


※ PPP_Unique family introduction

    Phosphoprotein phosphatase (PPP) is highly conserved among all eukaryotes. Seven phosphatases compose of PPP family in human genome, which are known as PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6 and PP7. PPP family phosphatases share a conserved catalytic domain ~280 amino acids and three signature motifs (-GDXHG-, -GDXVDRG- and -GNHE-) in its domain. The catalytic subunits of several members in PPP family always associate with a number of regulatory subunits, which regulate the substrate recognition and function. For PPP family members, metal ions play an important role during dephosphorylation reaction (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Php-0830
PP1S43_58V6
2
iEKPD-Php-g024
PP1S267_74V6
3
iEKPD-Php-0811
PP1S118_177V6
A9STZ7
PHYPADRAFT_135304
4
iEKPD-Php-g027
PP1S343_69V6
A9TW98
PHYPADRAFT_172337
5
iEKPD-Php-0927
PP1S412_38V6
A9U179
PHYPADRAFT_3832
6
iEKPD-Php-g020
PP1S116_170V6
A9STE1
PHYPADRAFT_58624