Saccharomyces cerevisiae      PPP/PPP_Unique


※ PPP_Unique family introduction

    Phosphoprotein phosphatase (PPP) is highly conserved among all eukaryotes. Seven phosphatases compose of PPP family in human genome, which are known as PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6 and PP7. PPP family phosphatases share a conserved catalytic domain ~280 amino acids and three signature motifs (-GDXHG-, -GDXVDRG- and -GNHE-) in its domain. The catalytic subunits of several members in PPP family always associate with a number of regulatory subunits, which regulate the substrate recognition and function. For PPP family members, metal ions play an important role during dephosphorylation reaction (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837


There are 5 genes.  Reviewed (3 or Unreviewed (2

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Sac-0160
YNR032W
P32838
PPG1
2
iEKPD-Sac-0158
YPL179W
P32945
PPQ1
3
iEKPD-Sac-0162
YML016C
P26570
PPZ1
4
iEKPD-Sac-g010
YLR361C
Q05924
DCR2
5
iEKPD-Sac-g001
YNL217W
P40152
YNL217W