※ PPP_Unique family introduction

    Phosphoprotein phosphatase (PPP) is highly conserved among all eukaryotes. Seven phosphatases compose of PPP family in human genome, which are known as PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6 and PP7. PPP family phosphatases share a conserved catalytic domain ~280 amino acids and three signature motifs (-GDXHG-, -GDXVDRG- and -GNHE-) in its domain. The catalytic subunits of several members in PPP family always associate with a number of regulatory subunits, which regulate the substrate recognition and function. For PPP family members, metal ions play an important role during dephosphorylation reaction (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837

  Reviewed (0)  or Unreviewed (11) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tra-4878	TRIAE_CS42_2AL_TGACv1_093925_AA0289480	W5AQW5
2		iEKPD-Tra-4897	TRIAE_CS42_2BL_TGACv1_129708_AA0393360	A0A1D5TW43
3		iEKPD-Tra-4911	TRIAE_CS42_2DL_TGACv1_158310_AA0515340	A0A1D5UII4
4		iEKPD-Tra-4950	TRIAE_CS42_3AS_TGACv1_212353_AA0700230	A0A1D5VLC3
5		iEKPD-Tra-5112	TRIAE_CS42_5DL_TGACv1_434038_AA1427730	A0A1D5ZQF7
6		iEKPD-Tra-5137	TRIAE_CS42_6AS_TGACv1_485648_AA1549560	W5GEZ0
7		iEKPD-Tra-5176	TRIAE_CS42_6DS_TGACv1_542843_AA1731440	W5H4B7
8		iEKPD-Tra-g037	TRIAE_CS42_4BL_TGACv1_321658_AA1063730	A0A1D5XLQ2
9		iEKPD-Tra-g010	TRIAE_CS42_5AL_TGACv1_376533_AA1238090	A0A1D5YMP6
10		iEKPD-Tra-g019	TRIAE_CS42_5BL_TGACv1_407697_AA1358910	A0A1D5ZC76
11		iEKPD-Tra-g023	TRIAE_CS42_5DL_TGACv1_433244_AA1406750	W5FZQ3