Pongo abelii      PTPLA/PTPLA


※ PTPLA family introduction

    PTPLA, Protein tyrosine phosphatase-like protein, contains protein tyrosine phosphatase-like proteins. Classical PTP is characterized by its signure motif CXXXXXR, however, the Arg to Pro(R/P) variation is found at active site in PTPLA. And PTPLA has been thought to play an important role in development, differentiation, and maintenance of a number of tissue types (1).

Reference
1. Uwanogho, D.A., Hardcastle, Z., Balogh, P., Mirza, G., Thornburg, K.L., Ragoussis, J. and Sharpe, P.T. (1999) Molecular cloning, chromosomal mapping, and developmental expression of a novel protein tyrosine phosphatase-like gene. Genomics, 62, 406-416. PMID: 10644438


There are 4 genes.  Reviewed (1 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Poa-0589
ENSPPYG00000013472.2
Q5RBK3
HACD2
2
iEKPD-Poa-0590
ENSPPYG00000002125.2
H2N9V9
HACD1
3
iEKPD-Poa-0592
ENSPPYG00000006569.2
A0A140TAW9
HACD3
4
iEKPD-Poa-0591
ENSPPYG00000019186.1
H2PS28
HACD4