Ailuropoda melanoleuca      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Aim-0363
ENSAMEG00000015539.1
G1MAL7
2
iEKPD-Aim-0245
ENSAMEG00000010526.1
G1LVN9
GUCY2C
3
iEKPD-Aim-0074
ENSAMEG00000002896.1
G1L886
GUCY2D
4
iEKPD-Aim-0438
ENSAMEG00000017985.1
G1MI24
GUCY2F
5
iEKPD-Aim-0402
ENSAMEG00000016872.1
G1MES5
LOC100476540
6
iEKPD-Aim-0279
ENSAMEG00000012126.1
G1M0C8
NPR1
7
iEKPD-Aim-0230
ENSAMEG00000009829.1
D2HAL2
NPR2