Astyanax mexicanus      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Asm-0002
ENSAMXG00000000032.1
W5JXJ2
2
iEKPD-Asm-0260
ENSAMXG00000008452.1
W5KM71
3
iEKPD-Asm-0276
ENSAMXG00000008839.1
W5KNG6
4
iEKPD-Asm-0349
ENSAMXG00000011429.1
W5KVX5
5
iEKPD-Asm-0362
ENSAMXG00000011882.1
W5KXE8
6
iEKPD-Asm-0408
ENSAMXG00000013352.1
W5L1M8
7
iEKPD-Asm-0415
ENSAMXG00000013583.1
W5L2B3
8
iEKPD-Asm-0479
ENSAMXG00000015515.1
W5L8E5
9
iEKPD-Asm-0483
ENSAMXG00000015646.1
W5L8F4
10
iEKPD-Asm-0535
ENSAMXG00000017498.1
W5LDW2
11
iEKPD-Asm-0559
ENSAMXG00000018355.1
W5LGE0
12
iEKPD-Asm-0611
ENSAMXG00000020243.1
W5LLX8