Canis familiaris      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Caf-0232
ENSCAFG00000010908.3
F1PXR1
2
iEKPD-Caf-0286
ENSCAFG00000013037.3
F1PAG3
GUCY2C
3
iEKPD-Caf-0362
ENSCAFG00000016906.2
F1PBE7
GUCY2D
4
iEKPD-Caf-0390
ENSCAFG00000018034.3
E2RL14
GUCY2F
5
iEKPD-Caf-0110
ENSCAFG00000005230.3
F1P7U7
LOC485179
6
iEKPD-Caf-0377
ENSCAFG00000017511.3
F1PMP1
NPR1
7
iEKPD-Caf-0052
ENSCAFG00000002233.6
F1PPT9
NPR2