Chlorocebus sabaeus      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Chs-0198
ENSCSAG00000008468.1
A0A0D9R7Y2
GUCY2C
2
iEKPD-Chs-0268
ENSCSAG00000011056.1
A0A0D9RF59
GUCY2D
3
iEKPD-Chs-0211
ENSCSAG00000008852.1
A0A0D9R919
GUCY2F
4
iEKPD-Chs-0033
ENSCSAG00000001869.1
A0A0D9S5M2
NPR1
5
iEKPD-Chs-0255
ENSCSAG00000010612.1
A0A0D9RDZ3
NPR2