Ciona savignyi      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Cis-0024
ENSCSAVG00000000846.1
H2Y840
2
iEKPD-Cis-0060
ENSCSAVG00000002369.1
H2YFA4
3
iEKPD-Cis-0062
ENSCSAVG00000002395.1
H2YFF7
4
iEKPD-Cis-0155
ENSCSAVG00000006815.1
H2Z204