Dipodomys ordii      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dio-0043
ENSDORG00000001588.2
A0A1S3EXA0
Gucy2d
2
iEKPD-Dio-0059
ENSDORG00000002237.2
A0A1S3FZ40
Gucy2f
3
iEKPD-Dio-0433
ENSDORG00000028075.1
A0A1S3FAK1
LOC105986609
4
iEKPD-Dio-0108
ENSDORG00000004886.2
A0A1S3F2G9
Npr1
5
iEKPD-Dio-0129
ENSDORG00000006262.2
A0A1S3G060
Npr2