Drosophila melanogaster      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 6 genes.  Reviewed (2 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Drm-0035
FBgn0010197
Q07553
Gyc32E
2
iEKPD-Drm-0193
FBgn0261360
Q7JQ32
Gyc76C
3
iEKPD-Drm-0131
FBgn0034568
Q8MLX0
CG3216
4
iEKPD-Drm-0171
FBgn0051183
Q9VF17
FBgn0038379
5
iEKPD-Drm-0139
FBgn0036368
Q9VU79
GYC
6
iEKPD-Drm-0180
FBgn0085386
A8JQT1
GYC