Erinaceus europaeus      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ere-0031
ENSEEUG00000001281.1
A0A1S3ADE9
GUCY2C
2
iEKPD-Ere-0236
ENSEEUG00000010329.1
A0A1S2ZRK9
GUCY2D
3
iEKPD-Ere-0273
ENSEEUG00000011992.1
A0A1S3AG26
GUCY2F
4
iEKPD-Ere-0251
ENSEEUG00000011148.1
A0A1S3WBN9
NPR2