Fukomys damarensis      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Fud-0010
ENSFDAG00000000739.1
A0A091DZ40
H920_02256
2
iEKPD-Fud-0282
ENSFDAG00000013434.1
A0A091DWA5
H920_03250
3
iEKPD-Fud-0447
ENSFDAG00000020323.1
A0A091DEQ4
H920_09638
4
iEKPD-Fud-0362
ENSFDAG00000016813.1
A0A091D9V2
H920_11383
5
iEKPD-Fud-0300
ENSFDAG00000014137.1
A0A091CNW4
H920_19759