Gasterosteus aculeatus      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Gaa-0033
ENSGACG00000000923.1
G3N7C9
2
iEKPD-Gaa-0040
ENSGACG00000001181.1
G3N8A2
3
iEKPD-Gaa-0094
ENSGACG00000003575.1
G3NH76
4
iEKPD-Gaa-0131
ENSGACG00000004649.1
G3NLD1
5
iEKPD-Gaa-0183
ENSGACG00000006407.1
G3NT14
6
iEKPD-Gaa-0216
ENSGACG00000007516.1
G3NXB3
7
iEKPD-Gaa-0285
ENSGACG00000009808.1
G3P5T2
8
iEKPD-Gaa-0298
ENSGACG00000010362.1
G3P7X8
9
iEKPD-Gaa-0511
ENSGACG00000018018.1
G3Q1Q8
10
iEKPD-Gaa-0529
ENSGACG00000018704.1
G3Q4C4
11
iEKPD-Gaa-0565
ENSGACG00000020398.1
G3QAP7