Gorilla gorilla      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Gog-0236
ENSGGOG00000010656.3
G3R542
GUCY2C
2
iEKPD-Gog-0345
ENSGGOG00000014330.3
G3REJ8
GUCY2D
3
iEKPD-Gog-0153
ENSGGOG00000006763.3
G3QV59
GUCY2F
4
iEKPD-Gog-0257
ENSGGOG00000011241.3
G3R6K8
NPR2