Ictidomys tridecemlineatus      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ict-0019
ENSSTOG00000000539.3
I3LWV3
GUCY2C
2
iEKPD-Ict-0004
ENSSTOG00000000149.3
I3LW24
GUCY2D
3
iEKPD-Ict-0370
ENSSTOG00000022009.2
I3N692
NPR1
4
iEKPD-Ict-0144
ENSSTOG00000006885.3
I3M8S4
NPR2