Lepisosteus oculatus      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Leo-0012
ENSLOCG00000001011.1
W5LYF1
2
iEKPD-Leo-0051
ENSLOCG00000002488.1
W5M3H3
3
iEKPD-Leo-0130
ENSLOCG00000005586.1
W5MED8
4
iEKPD-Leo-0168
ENSLOCG00000006899.1
W5MJ10
5
iEKPD-Leo-0266
ENSLOCG00000010458.1
W5MWT5
6
iEKPD-Leo-0307
ENSLOCG00000011647.1
W5N106
7
iEKPD-Leo-0329
ENSLOCG00000012255.1
W5N379
8
iEKPD-Leo-0364
ENSLOCG00000013396.1
W5N7C1
9
iEKPD-Leo-0395
ENSLOCG00000014403.1
W5NAU0