Loxodonta africana      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Loa-0456
ENSLAFG00000030179.1
G3U1X3
2
iEKPD-Loa-0120
ENSLAFG00000005831.3
G3SWZ7
GUCY2C
3
iEKPD-Loa-0129
ENSLAFG00000006345.3
G3SY06
GUCY2D
4
iEKPD-Loa-0130
ENSLAFG00000006374.3
G3SY26
GUCY2F
5
iEKPD-Loa-0055
ENSLAFG00000002661.2
G3SQX1
NPR1
6
iEKPD-Loa-0305
ENSLAFG00000015001.3
G3TEA4
NPR2