Macaca mulatta      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Mam-0299
ENSMMUG00000017723.3
F7F8P7
GUCY2D
2
iEKPD-Mam-0216
ENSMMUG00000013199.3
F6XGE4
GUCY2F
3
iEKPD-Mam-0130
ENSMMUG00000008153.3
F7HE88
NPR1
4
iEKPD-Mam-0270
ENSMMUG00000016334.3
F7GRM1
NPR2