※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC

  Reviewed (0)  or Unreviewed (6) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mod-0100	ENSMODG00000005266.3	F7GGN7
2		iEKPD-Mod-0377	ENSMODG00000018193.3	F7B751
3		iEKPD-Mod-0137	ENSMODG00000007621.3	F7C549	GUCY2D
4		iEKPD-Mod-0089	ENSMODG00000004608.3	F6Y3Q3	LOC100024379
5		iEKPD-Mod-0216	ENSMODG00000010281.3	F6VNS7	LOC100027754
6		iEKPD-Mod-0128	ENSMODG00000007007.3	F6XTY3	NPR2