Mustela putorius furo      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Muf-0213
ENSMPUG00000008573.1
M3YAZ9
2
iEKPD-Muf-0283
ENSMPUG00000011623.1
M3YJM4
GUCY2C
3
iEKPD-Muf-0216
ENSMPUG00000008642.1
M3YB67
GUCY2D
4
iEKPD-Muf-0200
ENSMPUG00000008249.1
M3YA30
NPR1
5
iEKPD-Muf-0139
ENSMPUG00000005513.1
M3Y2C0
NPR2