Myotis lucifugus      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Myl-0021
ENSMLUG00000001171.2
G1NUZ2
2
iEKPD-Myl-0140
ENSMLUG00000006258.2
G1PYN2
3
iEKPD-Myl-0442
ENSMLUG00000025177.1
G1Q561
4
iEKPD-Myl-0084
ENSMLUG00000003624.2
G1P0L6
GUCY2C
5
iEKPD-Myl-0410
ENSMLUG00000017406.2
G1PWT5
GUCY2D
6
iEKPD-Myl-0038
ENSMLUG00000001852.2
G1NWH9
NPR1
7
iEKPD-Myl-0265
ENSMLUG00000011640.2
G1Q866
NPR2