Nomascus leucogenys      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Nol-0106
ENSNLEG00000003853.3
G1QUW6
GUCY2C
2
iEKPD-Nol-0239
ENSNLEG00000009820.2
G1RFH3
GUCY2D
3
iEKPD-Nol-0339
ENSNLEG00000014307.2
G1RVX3
GUCY2F
4
iEKPD-Nol-0254
ENSNLEG00000010560.2
G1RHZ0
NPR1
5
iEKPD-Nol-0111
ENSNLEG00000004067.2
G1QVM9
NPR2