Ochotona princeps      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ocp-0096
ENSOPRG00000003749.1
2
iEKPD-Ocp-0329
ENSOPRG00000012893.1
3
iEKPD-Ocp-0372
ENSOPRG00000014679.1
4
iEKPD-Ocp-0380
ENSOPRG00000014943.1
5
iEKPD-Ocp-0412
ENSOPRG00000016246.1