※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC

  Reviewed (0)  or Unreviewed (7) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Ora-0022	ENSOANG00000001116.3	F6WLZ7
2		iEKPD-Ora-0029	ENSOANG00000001586.2	F7F1F1
3		iEKPD-Ora-0182	ENSOANG00000008317.1	F6QH46
4		iEKPD-Ora-0409	ENSOANG00000021513.2	F6RYN1
5		iEKPD-Ora-0157	ENSOANG00000007339.2	F6W2A3	GUCY2C
6		iEKPD-Ora-0290	ENSOANG00000012129.2	F7E506	LOC100078016
7		iEKPD-Ora-0112	ENSOANG00000005200.3	F7C6G4	NPR2