Oryctolagus cuniculus      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Orc-0169
ENSOCUG00000008162.3
G1SUM0
GUCY2C
2
iEKPD-Orc-0093
ENSOCUG00000004872.2
G1SMP7
GUCY2D
3
iEKPD-Orc-0199
ENSOCUG00000009664.2
G1SXP0
GUCY2F
4
iEKPD-Orc-0400
ENSOCUG00000023136.2
G1TFP9
LOC100344092
5
iEKPD-Orc-0442
ENSOCUG00000027588.2
G1TXB5
NPR1
6
iEKPD-Orc-0124
ENSOCUG00000006453.2
G1SR19
NPR2