Oryzias latipes      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ore-0407
ENSORLG00000014359.1
H2MHA2
2
iEKPD-Ore-0564
ENSORLG00000020832.1
H2N2V8
3
iEKPD-Ore-g011
ENSORLG00000018002.1
H2MUS5
4
iEKPD-Ore-0328
ENSORLG00000011732.1
H2M894
LOC101172201
5
iEKPD-Ore-0388
ENSORLG00000013710.1
H2MF31
npr2
6
iEKPD-Ore-0275
ENSORLG00000009512.2
H2M0K5
olgc-r2
7
iEKPD-Ore-0218
ENSORLG00000007868.1
H2LUT3
olgc5
8
iEKPD-Ore-0077
ENSORLG00000002713.1
H2LBV6
olgc6
9
iEKPD-Ore-0044
ENSORLG00000001459.1
H2L7J3
olgc7
10
iEKPD-Ore-0061
ENSORLG00000002179.1
H2LA11
olgc8
11
iEKPD-Ore-0402
ENSORLG00000014236.1
H2MGW7
olgc9