Pan paniscus      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pap-0050
ENSPPAG00000024389.1
2
iEKPD-Pap-0151
ENSPPAG00000030573.1
3
iEKPD-Pap-0261
ENSPPAG00000035430.1
4
iEKPD-Pap-0346
ENSPPAG00000038449.1
5
iEKPD-Pap-0454
ENSPPAG00000042967.1