Papio anubis      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Paa-0403
ENSPANG00000023806.2
A0A096NW95
GUCY2C
2
iEKPD-Paa-0404
ENSPANG00000023931.2
A0A096P2T1
GUCY2D
3
iEKPD-Paa-0161
ENSPANG00000011773.2
A0A096NFG5
GUCY2F
4
iEKPD-Paa-0336
ENSPANG00000021848.2
A0A2I3MU35
NPR1
5
iEKPD-Paa-0444
ENSPANG00000025560.2
A0A096P169
NPR2