Pelodiscus sinensis      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pes-0150
ENSPSIG00000007899.1
K7FL18
2
iEKPD-Pes-0195
ENSPSIG00000009447.1
K7FQV5
3
iEKPD-Pes-0375
ENSPSIG00000016238.1
K7GDY6
GUCY2C
4
iEKPD-Pes-0164
ENSPSIG00000008359.1
K7FMX4
GUCY2D