Petromyzon marinus      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pem-0001
ENSPMAG00000000040.1
S4R4B4
2
iEKPD-Pem-0017
ENSPMAG00000000869.1
S4R6X2
3
iEKPD-Pem-0057
ENSPMAG00000002416.1
S4RBQ7
4
iEKPD-Pem-0090
ENSPMAG00000003471.1
S4REZ6
5
iEKPD-Pem-0137
ENSPMAG00000005587.1
S4RM87
6
iEKPD-Pem-0216
ENSPMAG00000008084.1
S4RUL3
7
iEKPD-Pem-0217
ENSPMAG00000008096.1
S4RUP6
8
iEKPD-Pem-0229
ENSPMAG00000008445.1
S4RVR1