Pongo abelii      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Poa-0084
ENSPPYG00000004320.2
H2NGP2
GUCY2C
2
iEKPD-Poa-0170
ENSPPYG00000007945.1
H2NSM1
GUCY2D
3
iEKPD-Poa-0447
ENSPPYG00000020624.1
H2PWG8
GUCY2F
4
iEKPD-Poa-0023
ENSPPYG00000000799.2
H2N5N2
NPR1
5
iEKPD-Poa-0422
ENSPPYG00000019083.2
H2PRS0
NPR2