Sarcophilus harrisii      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Sah-0096
ENSSHAG00000006091.1
G3VV04
2
iEKPD-Sah-0430
ENSSHAG00000018403.1
G3X228
3
iEKPD-Sah-0389
ENSSHAG00000017101.1
G3WXK5
GUCY2C
4
iEKPD-Sah-0309
ENSSHAG00000013941.1
G3WLS8
GUCY2D
5
iEKPD-Sah-0197
ENSSHAG00000010248.1
G3W938
NPR1
6
iEKPD-Sah-0312
ENSSHAG00000013983.1
G3WLY4
NPR2