※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC

  Reviewed (0)  or Unreviewed (7) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sus-0407	ENSSSCG00000031896.1	A0A287B8Q2
2		iEKPD-Sus-0409	ENSSSCG00000031998.1	A0A287A4A4
3		iEKPD-Sus-0364	ENSSSCG00000026724.2	I3LJ94	GUCY2C
4		iEKPD-Sus-0350	ENSSSCG00000025345.2	I3LJL1	GUCY2D
5		iEKPD-Sus-0218	ENSSSCG00000012580.3	A0A287AU99	GUCY2F
6		iEKPD-Sus-0101	ENSSSCG00000006572.3	F1SFW3	NPR1
7		iEKPD-Sus-0083	ENSSSCG00000005322.3	F1STB3	NPR2