※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC

  Reviewed (0)  or Unreviewed (5) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tag-0385	ENSTGUG00000013060.1	H0ZS59
2		iEKPD-Tag-g016	ENSTGUG00000015156.1	H0ZXZ6
3		iEKPD-Tag-0293	ENSTGUG00000009506.1	H0ZGX2	GUCY2C
4		iEKPD-Tag-0051	ENSTGUG00000001308.1	H0YST7	LOC100231322
5		iEKPD-Tag-0073	ENSTGUG00000001828.1	H0YUC4	NPR2