※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC

  Reviewed (0)  or Unreviewed (11) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tar-0574	ENSTRUG00000017524.1	H2V6T6
2		iEKPD-Tar-0143	ENSTRUG00000004638.1	H2SF42	gucy2c
3		iEKPD-Tar-0339	ENSTRUG00000010360.1	H2TN28	LOC101062907
4		iEKPD-Tar-0050	ENSTRUG00000001740.1	H2RV09	LOC101068241
5		iEKPD-Tar-0552	ENSTRUG00000017007.1	H2V2V9	LOC101069264
6		iEKPD-Tar-0029	ENSTRUG00000000936.1	H2RQ13	LOC101072043
7		iEKPD-Tar-0225	ENSTRUG00000006996.1	H2SXP3	LOC101072371
8		iEKPD-Tar-0529	ENSTRUG00000016388.1	H2UY61	LOC101072570
9		iEKPD-Tar-0265	ENSTRUG00000008278.1	H2T7S0	LOC101073658
10		iEKPD-Tar-0360	ENSTRUG00000010872.1	H2TS21	LOC101074483
11		iEKPD-Tar-0290	ENSTRUG00000008848.1	H2TC35	LOC101074569