※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC

  Reviewed (0)  or Unreviewed (12) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Ten-0075	ENSTNIG00000003180.1	H3CBY8
2		iEKPD-Ten-0092	ENSTNIG00000003628.1	H3CDA0
3		iEKPD-Ten-0093	ENSTNIG00000003648.1	H3C454
4		iEKPD-Ten-0126	ENSTNIG00000004620.1	H3CG94
5		iEKPD-Ten-0144	ENSTNIG00000005206.1	H3C6S4
6		iEKPD-Ten-0154	ENSTNIG00000005759.1	H3CJP6
7		iEKPD-Ten-0161	ENSTNIG00000006188.1	H3CL07
8		iEKPD-Ten-0349	ENSTNIG00000011768.1	H3D2I2
9		iEKPD-Ten-0384	ENSTNIG00000012936.1	H3D5X6
10		iEKPD-Ten-0433	ENSTNIG00000014416.1	H3DA93
11		iEKPD-Ten-0482	ENSTNIG00000015553.1	H3DDN2
12		iEKPD-Ten-0065	ENSTNIG00000002860.1	H3CB04	GUCY2D