Xenopus tropicalis      RGC/RGC


※ RGC family introduction

    RGCs are Receptor Guanylate Cyclases that have an unusual structure: they are single-pass transmembrane receptors that have an active guanylate cyclase domain and a catalytically inactive kinase domain on the intracellular side. The guanylate cyclase domain makes the second messenger cGMP, and the kinase domain may have a regulatory role and may bind ATP (1,2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation:    Kinase Group RGC


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Xet-0310
ENSXETG00000014729.3
F7DQ86
2
iEKPD-Xet-0552
ENSXETG00000030113.1
F7BRU0
3
iEKPD-Xet-0274
ENSXETG00000013430.3
F7BYS9
gucy2c
4
iEKPD-Xet-0176
ENSXETG00000009074.3
F7BRK6
gucy2d
5
iEKPD-Xet-0040
ENSXETG00000001567.3
F6XL31
gucy2f
6
iEKPD-Xet-0294
ENSXETG00000014291.3
F6R6S1
npr1
7
iEKPD-Xet-0381
ENSXETG00000018799.2
F6XYF1
npr2