Aspergillus nidulans      STE/STE11


※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 5 genes.  Reviewed (1 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Asa-0069
CADANIAG00006073
Q5B4Z3
sepH
2
iEKPD-Asa-0108
CADANIAG00008961
G5EB26
ANIA_02269
3
iEKPD-Asa-0060
CADANIAG00005516
C8V9T1
ANIA_04887
4
iEKPD-Asa-0076
CADANIAG00006503
C8V064
ANIA_10819
5
iEKPD-Asa-0016
CADANIAG00001446
C8VT14
sskB