Neurospora crassa      STE/STE11


※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Nec-0017
NCU01335
Q1K7U1
cdc15
2
iEKPD-Nec-0027
NCU02234
V5ILP2
mik-1
3
iEKPD-Nec-0104
NCU08414
Q7SC40
NCU08414
4
iEKPD-Nec-0073
NCU06182
Q7RVY6
nrc-1
5
iEKPD-Nec-0032
NCU03071
Q1K904
os-4