Xenopus tropicalis      STE/STE11


※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Xet-0158
ENSXETG00000008257.5
F6X5R9
2
iEKPD-Xet-0320
ENSXETG00000015513.3
F6YLG8
map3k1
3
iEKPD-Xet-0114
ENSXETG00000006210.3
F7CY76
map3k15
4
iEKPD-Xet-0017
ENSXETG00000000471.3
F7ENM6
map3k2
5
iEKPD-Xet-0369
ENSXETG00000018442.3
F6VVX1
map3k3
6
iEKPD-Xet-0054
ENSXETG00000002476.3
F7A415
map3k5