Homo sapiens      STE/STE7


※ STE7 family introduction

    STE7 (MAP2K, MEK) kinases participate in the MAPK signaling cascades, STE7s are activated by STE11 and subsequent mediate the phosphorylation of MAPK kinases. STE7 are typical dual-specificity kinases and can phosphorylate the conserved TxY motif on MAPK. STE7 can further be classified into five subclasses: MEK1, MEK3, MEK4, MEK5 and MEK7 (1).

Reference
1. Wikinome Annotation:   Kinase Family STE7


There are 7 genes.  Reviewed (7 or Unreviewed (0

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Hos-0356
ENSG00000169032.9
Q02750
MAP2K1; MEK1; PRKMK1
2
iEKPD-Hos-0191
ENSG00000126934.13
P36507
MAP2K2; MEK2; MKK2; PRKMK2
3
iEKPD-Hos-0020
ENSG00000034152.18
P46734
MAP2K3; MEK3; MKK3; PRKMK3; SKK2
4
iEKPD-Hos-0041
ENSG00000065559.14
P45985
MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1
5
iEKPD-Hos-0235
ENSG00000137764.19
Q13163
MAP2K5; MEK5; MKK5; PRKMK5
6
iEKPD-Hos-0136
ENSG00000108984.13
P52564
MAP2K6; MEK6; MKK6; PRKMK6; SKK3
7
iEKPD-Hos-0069
ENSG00000076984.17
O14733
MAP2K7; JNKK2; MEK7; MKK7; PRKMK7; SKK4