Amborella trichopoda      TK/Fer


※ Fer family introduction

    Fer is nonontransmembrane receptor tyrosine kinases accepting the signal from cell surface receptors including EGFR, PDGFRA and PDGFRB and regulating a variety of cell processes. Interaction with EGFR will lead to the activation of NF-kappa-B pathway and cell proliferation. Fer can act as a downstream protein of activated FCER1 receptor and plays an important role in FCER1-mediated signaling in mast cells. Fer can also mediate phosphorylation of several substrates including, CTNND1, CTTN, PTK2/FAK1, PECAM1, GAB1 and PTPN11 (1).

Reference
1. UniProt Annotation:     FER_HUMAN


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Amt-0076
AMTR_s00007p00179040
W1PE48
AMTR_s00007p00179040
2
iEKPD-Amt-0101
AMTR_s00009p00261870
W1NI58
AMTR_s00009p00261870
3
iEKPD-Amt-0190
AMTR_s00019p00228390
W1PBP6
AMTR_s00019p00228390
4
iEKPD-Amt-0663
AMTR_s00174p00063700
U5CWH9
AMTR_s00174p00063700