Brachypodium distachyon TK/Fer
※ Fer family introduction Fer is nonontransmembrane receptor tyrosine kinases accepting the signal from cell surface receptors including EGFR, PDGFRA and PDGFRB and regulating a variety of cell processes. Interaction with EGFR will lead to the activation of NF-kappa-B pathway and cell proliferation. Fer can act as a downstream protein of activated FCER1 receptor and plays an important role in FCER1-mediated signaling in mast cells. Fer can also mediate phosphorylation of several substrates including, CTNND1, CTTN, PTK2/FAK1, PECAM1, GAB1 and PTPN11 (1). Reference
1. UniProt Annotation: FER_HUMAN
There are 12 genes. Reviewed (0)
or Unreviewed (12) 
※ Fer family introduction Fer is nonontransmembrane receptor tyrosine kinases accepting the signal from cell surface receptors including EGFR, PDGFRA and PDGFRB and regulating a variety of cell processes. Interaction with EGFR will lead to the activation of NF-kappa-B pathway and cell proliferation. Fer can act as a downstream protein of activated FCER1 receptor and plays an important role in FCER1-mediated signaling in mast cells. Fer can also mediate phosphorylation of several substrates including, CTNND1, CTTN, PTK2/FAK1, PECAM1, GAB1 and PTPN11 (1). Reference
1. UniProt Annotation: FER_HUMAN
There are 12 genes. Reviewed (0)
or Unreviewed (12) | No. | Status | iEKPD ID | Ensemble Gene ID | UniProt Accession | Gene Name |
|---|---|---|---|---|---|
| 1 | | ||||
| 2 | | ||||
| 3 | | ||||
| 4 | | ||||
| 5 | | ||||
| 6 | | ||||
| 7 | | ||||
| 8 | | ||||
| 9 | | ||||
| 10 | | ||||
| 11 | | ||||
| 12 | |