Caenorhabditis elegans      TK/Fer


※ Fer family introduction

    Fer is nonontransmembrane receptor tyrosine kinases accepting the signal from cell surface receptors including EGFR, PDGFRA and PDGFRB and regulating a variety of cell processes. Interaction with EGFR will lead to the activation of NF-kappa-B pathway and cell proliferation. Fer can act as a downstream protein of activated FCER1 receptor and plays an important role in FCER1-mediated signaling in mast cells. Fer can also mediate phosphorylation of several substrates including, CTNND1, CTTN, PTK2/FAK1, PECAM1, GAB1 and PTPN11 (1).

Reference
1. UniProt Annotation:     FER_HUMAN


There are 34 genes.  Reviewed (2 or Unreviewed (32

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Cae-0797
WBGene00001487
Q22146
frk-1
2
iEKPD-Cae-0807
WBGene00004962
O01798
spe-8
3
iEKPD-Cae-0275
WBGene00015994
Q9GZG1
C18H7.4
4
iEKPD-Cae-0822
WBGene00016085
Q18142
C25A8.5
5
iEKPD-Cae-0824
WBGene00016462
H2KZ80
C35E7.10
6
iEKPD-Cae-0825
WBGene00016954
Q18865
C55C3.4
7
iEKPD-Cae-0188
WBGene00009039
Q19704
CELE_F22B3.8
8
iEKPD-Cae-0826
WBGene00017736
Q9TXI2
CELE_F23C8.7
9
iEKPD-Cae-0810
WBGene00009160
O01325
CELE_F26E4.5
10
iEKPD-Cae-0827
WBGene00018999
Q20933
CELE_F57B9.8
11
iEKPD-Cae-0828
WBGene00019081
P91360
CELE_F59A3.8
12
iEKPD-Cae-0811
WBGene00010712
Q9U3B5
CELE_K09B11.5
13
iEKPD-Cae-0821
WBGene00014813
A0A0S4FT70
CELE_M176.9
14
iEKPD-Cae-0211
WBGene00011039
Q21764
CELE_R05H5.4
15
iEKPD-Cae-0347
WBGene00020003
Q9TYX4
CELE_R11E3.1
16
iEKPD-Cae-0829
WBGene00020289
Q22243
CELE_T06C10.3
17
iEKPD-Cae-0360
WBGene00020659
O02064
CELE_T21G5.1
18
iEKPD-Cae-0813
WBGene00012010
Q22765
CELE_T25B9.4
19
iEKPD-Cae-0814
WBGene00012011
A0A061ADQ6
CELE_T25B9.5
20
iEKPD-Cae-0815
WBGene00012172
Q23102
CELE_W01B6.5
21
iEKPD-Cae-0362
WBGene00020966
Q23136
CELE_W03A5.1
22
iEKPD-Cae-0818
WBGene00013801
H8ESG3
CELE_Y116A8C.24
23
iEKPD-Cae-0819
WBGene00013811
Q9U2T8
CELE_Y116A8C.38
24
iEKPD-Cae-0816
WBGene00012785
Q9XXE5
CELE_Y43C5B.2
25
iEKPD-Cae-0831
WBGene00021793
Q9N4S6
CELE_Y52D5A.2
26
iEKPD-Cae-0817
WBGene00013475
Q9XW34
CELE_Y69E1A.3
27
iEKPD-Cae-0383
WBGene00022634
O01774
CELE_ZC581.7
28
iEKPD-Cae-0832
WBGene00022780
Q23554
CELE_ZK622.1
29
iEKPD-Cae-0799
WBGene00002198
Q19726
kin-14
30
iEKPD-Cae-0073
WBGene00002204
G5EBM6
kin-21
31
iEKPD-Cae-0800
WBGene00002206
D6R8W4
kin-24
32
iEKPD-Cae-0801
WBGene00002208
Q22245
kin-26
33
iEKPD-Cae-0798
WBGene00002193
G5EC46
kin-5
34
iEKPD-Cae-0066
WBGene00002194
Q8I4A8
kin-6