※ Fer family introduction

    Fer is nonontransmembrane receptor tyrosine kinases accepting the signal from cell surface receptors including EGFR, PDGFRA and PDGFRB and regulating a variety of cell processes. Interaction with EGFR will lead to the activation of NF-kappa-B pathway and cell proliferation. Fer can act as a downstream protein of activated FCER1 receptor and plays an important role in FCER1-mediated signaling in mast cells. Fer can also mediate phosphorylation of several substrates including, CTNND1, CTTN, PTK2/FAK1, PECAM1, GAB1 and PTPN11 (1).

Reference
1. UniProt Annotation:     FER_HUMAN

  Reviewed (0)  or Unreviewed (4) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Nia-0640	A4A49_53889	A0A1J6I5B2	LECRK92
2		iEKPD-Nia-0593	A4A49_39533	A0A1J6JG59	LRK10_9
3		iEKPD-Nia-0630	A4A49_43691	A0A1J6K9I0	RLK1_1
4		iEKPD-Nia-0639	A4A49_53631	A0A1J6HVF8	WAKL2