Physcomitrella patens      TK/Fer


※ Fer family introduction

    Fer is nonontransmembrane receptor tyrosine kinases accepting the signal from cell surface receptors including EGFR, PDGFRA and PDGFRB and regulating a variety of cell processes. Interaction with EGFR will lead to the activation of NF-kappa-B pathway and cell proliferation. Fer can act as a downstream protein of activated FCER1 receptor and plays an important role in FCER1-mediated signaling in mast cells. Fer can also mediate phosphorylation of several substrates including, CTNND1, CTTN, PTK2/FAK1, PECAM1, GAB1 and PTPN11 (1).

Reference
1. UniProt Annotation:     FER_HUMAN


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Php-0126
PP1S149_117V6
2
iEKPD-Php-0128
PP1S149_95V6
3
iEKPD-Php-0262
PP1S201_20V6
4
iEKPD-Php-0432
PP1S2_235V6
5
iEKPD-Php-g008
PP1S202_76V6
6
iEKPD-Php-0573
PP1S409_25V6
A9U0Z5
PHYPADRAFT_100079
7
iEKPD-Php-0279
PP1S208_95V6
A9TD98
PHYPADRAFT_91272