※ Fer family introduction

    Fer is nonontransmembrane receptor tyrosine kinases accepting the signal from cell surface receptors including EGFR, PDGFRA and PDGFRB and regulating a variety of cell processes. Interaction with EGFR will lead to the activation of NF-kappa-B pathway and cell proliferation. Fer can act as a downstream protein of activated FCER1 receptor and plays an important role in FCER1-mediated signaling in mast cells. Fer can also mediate phosphorylation of several substrates including, CTNND1, CTTN, PTK2/FAK1, PECAM1, GAB1 and PTPN11 (1).

Reference
1. UniProt Annotation:     FER_HUMAN

  Reviewed (0)  or Unreviewed (3) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sob-0773	SORBI_3005G175200	A0A1B6PT58	SORBI_3005G175200
2		iEKPD-Sob-0796	SORBI_3005G220800	A0A1Z5RJW3	SORBI_3005G220800
3		iEKPD-Sob-1007	SORBI_3008G065200	A0A1Z5R574	SORBI_3008G065200